| Awards & Awardees |
| JSPC Award for Excellence |
| Recognizes notable contributions to process chemistry. The awardees will be selected as a research group from the general presentation at the summer symposium. The award consists of a testimonial shield and the awardee should represent their research works at the appropriate symposium. |
| Awardees |
| 2011 | |
One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether Hayato Ishikawa, Masakazu Honma, Yujiro Hayashi* (Tokyo University of Science, Japan) |
Development of a practical synthesis for HDAC Inhibitor AS1623879-CL Ryoki Orii*, Takashi Kikuchi (Astellas Pharma Inc., Japan) |
Development of a Novel Liquid-Phase Peptide Synthesis (LPPS) on Anchors Bearing a Long Aliphatic Chain: AJI-PHASETM Daisuke Takahashi* (AJINOMOTO Co., Inc. Japan) |
Asymmetric Synthesis of Allyl Esters via Vanadium-Lipase Combo Catalyzed Dynamic Kinetic Resolution. Masahiro Egi1), Koji Sugiyma1)*, Moriaki Saneto1), Ryosuke Hanada1), Katsuya Kato2), Shuji Akai1) [(1)University of Shizuoka, Japan, (2)National Institute of Advanced Industrial Science and Techology, Japan] |
| 2010 |
| Shunsuke Fukuya*, Michiharu Handa, Katsuya Sakata, Hiroyuki Kotajima, Motoi Otani (Onda Plant, Technical Deveropment Division, Nissan Chemical Industries, Ltd., Japan) Process deveropment of AZADO-catalyzed oxidation - Experimental demonstration by pirot scale production - |
| Hirofumi Maeda*, Akio Fujii, Masaru Mitsuda (Frontier Biochemical& Medical Research Labratories, Kaneka Corporation, Japan) Deveropment of Novel Phosphoramidite Monomer for Oligo RNA Synthesis |
| Yutaka Saga*, Rie Motoki, Sae Makino, Yohei Shimizu, Motomu Kanai, Masakatsu Shibasaki (Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan) Catalytic Asymmetric Synthesis of R207910 |
| 2009 | |
Shinpei Iida, Ryosuke Ohmura, Hideo Togo* (Graduate School of Science, Chiba University, Japan) Direct Oxidative Conversion of Alcohols, Amines, and Alkyl halides into Nitriles with Molecular Iodine and 1,3-Diiodo-5,5-dimethylhydantoin in aq. Ammonia. |
Kaichiro Koyama*, Hitoshi Shimizu, Shinichi Ebihara (synthetic Technology Research Dept., Chugai Pharmaceutical & Co., Ltd., Japan) Optimization of drying process in scale-up manufacturing for Erythromycin A derivative. |
| Osamu Ogata*, Yasunori Ino, Wataru Kuriyama, Takaji Matsumoto (Corporate research & Development Division, Takasago International Corporation, Japan) An Efficient Synthesis of Chiral Alcohols via Catalytic Hydrogen Reduction of Esters. |
| Hiromichi Fujioka, Kento Senami*, Ozora Kubo, Yutaka Minamitsuji, Tomohiro Maegawa (Graduate School of Pharmaceutical Sciences, Osaka University, Japan) Development of very mild and highly selective deprotection method of methylene acetals. |
| 2008 |
| Arata Yanagisawa*, Koichiro Nishimura ,Tetsuya Nezu, Kyoji Ando, Ayako
Maki, Eiichiro Imai, Shin-ichiro Mohri (Kyowa Hakko Kogyo, Japan) A Practical Synthesis of the PDE4 inhibitor KW-4490. |
| Takashi Inaba*, Masahiro Tanaka, Minoru Ubukata, Takafumi Matsuo, Katsutaka
Yasue, Katsuya Matsumoto, Yasuyuki Kajimoto, Takashi Ogo (Japan Tobacco
Inc.,Japan) An Efficient Synthesis of the PKCb Inhibitor JTT-010 Using a Novel Cyclopropane Ring-Opening Reaction with Indole |
| Takashi Ohshima*, Takanori Iwasaki, Yusuke Maegawa, Yukiko Hayashi, Kazushi
Mashima (Osaka University, Japan) Development of Protecting Group Free Catalytic O-Selective Acylation of Aminoalcohols |
| Kiwon Han*, Yoon Kyung Choi, Cheolwoo Kim, Jaiwook Park, Mahn-Joo Kim (POSTECH,
Korea) Dynamic Kinetic Resolution of Primary Amines by Lipase-Palladium Cocatalysis |
| 2007 |
| Tetsuya Ikemoto, Yosuke Watanabe, Junichi Tomokawa, Takehiko Kawakami,
Yasuo Uekita, and Isao Kurimoto (Sumitomo Chemical Co.) Process development of a key building block for anti-AIDS drugs by proline catalyzed enantioselective direct cross aldol reaction |
| Hideo Nagashima, Hidehiro Sasakuma, Nariaki Harada, Hironori Tsutsumi,
and Yukihiro Motoyama (Kyushu Univ.) Development of practical and scalable synthesis of triruthenium cluster catalyst and amide-selective silane reduction |
| Katsuo Oda, Toshiaki Masui, Hideo Nogusa, and Takemasa Hida (Shionogi)
Development of process route for the new antiarthritic drug S-2474 |
| 2006 |
| Ariyoshi Kubota, Koji Mukai, Shunsuke Goto, and Hironobu Yasuda (Astellas
Pharma) Interesting characteristics and their control of polymorphs of bradykinin antagonist FR173657 |
| Yumiko Okada, Shohei Yasuda, Jun Irie, Masaaki Takahashi, and Hitoshi Yamaguchi
(Meiji Seika) Manufacturing process development of tricyclic triazolobenzazepine derivative |
| Yoshiharu Iwabuchi, Masatoshi Shibuya, Masaki Tomizawa, Takamune Hattori,
and Takahisa Satoh (Tohoku Univ.) Development of 1-methyl-AZADO: a highly efficient organocatalyst for oxidation of alcohols |
| 2005 |
| Shintaro Kanazawa and Ichiro Araya (Kyorin) Practical process developments of KRP-103 for treatment of urinary incontinence |
| Masahiro Nagase, Mitsuhiro Kurita, Takemi Tanokura, Motoki Shimizu, Yoshiaki
Kato, Kunio Tamura, Hirohito Shimizu, and Masahiro Kato (Chugai) Process development of BO-653 for large scale production |
| Satomi Niwayama (Texas Tech Univ., USA) Practical monohydrolysis of symmetric diesters |
| Shuji Akai, Kouichi Tanimoto, Yukiko Kanao, Sohei Omura, and Yasuyuki Kita
(Osaka Univ.) Lipase-catalyzed domino-type asymmetric construction of carbon frameworks: One-step synthesis of optically active polysubstituted isoxazolidines |
| 2004 |
| Ryohei Nagase, Naoki Manta, Tomonori Misaki, and Yoo Tanabe (Kwansei Gakuin
Univ.) Makoto Sunagawa and Akira Sasaki (Sumitomo Pharmaceutical Co.) Practical synthesis of 1b-methylcarbapenem utilizing a new dehydration Ti-Dieckmann condensation |
| Yuuichi Katou, Tsutomu Sugawara, and Kazumi Okada (Nippon Kasei) Resolution technology of racemic mixtures using distillation technique in industrial scale |
| Takahiro Okachi and Katsuhiko Fujimoto (Sankyo) Practical promotion system for carbonyl-ene reactions styrenes with paraformaldehyde - The combined use of boron trifluoride and molecular sieves |
| 2003 |
| Shunsuke Goto, Hiroyuki Tsuboi, Atsuo Yamanaka, Kouji Mukai, and Kooji
Kagara (Fujisawa) Process development of FK664: A potent cardiotonic agent |
| Mikio Kabaki and Haruo Koike (Shionogi) Process development of gastrointestinal ulser therapeutic agent S-0509 |
| Takashi Ikawa, Hironao Sajiki, and Kosaku Hirota (Gifu Pharmaceutical Univ.)
Environmental friendly mono-alkylation of aromatic amine derivatives |
| 2002 |
| Masaya Ikunaka, Yoshito Fujima, Toru Inoue, and Keisuke Matsuyama (Nagase)
Shiro Kato, Hiroshi Harada, and Akihito Fujii (Dainippon) Synthesis of (R)-3-(2-aminopropyl)-7-benzyloxyindole, a key intermediate of antidiabetic AJ-9677, via optical resolution |
| Yuusaku Yokoyama, Hidemasa Hikawa, Masaharu Mitsuhashi, Yasuhiro Hiroki,
and Yasuoki Murakami (Toho Univ.) Synthesis without protection: Total synthesis of optically active clavicipitic acids utilizing a reaction of free amino acid |
| Youichi Matsumoto, Takeshi Murakami, and Yuuki Takuma (Mitsubishi Chemical
Corporation) Study on the preparation of a chiral aminofuranone derivatives for antirheumatic agents |